List of Publications on aHUS

SubjectLeadYearTitleLinkTypeFree
Causes Krishnappa V. 2017 Atypical Hemolytic Uremic Syndrome: A Meta-Analysis of Case Reports Confirms the Prevalence of Genetic Mutations and the Shift of Treatment Regimens https://www.ahusallianceaction.org/wp-content/uploads/2017/12/Krishnappa_et_al-2017-Therapeutic_Apheresis_and_Dialysis.pdf Meta-analysis yes
Treatment Van de Walle 2017 Improved renal recovery in patients with atypical hemolytic uremic syndrome following rapid initiation of eculizumab treatment. https://www.ncbi.nlm.nih.gov/pubmed/26995002 Case studies yes
Overview Yoshida 2017 Atypical hemolytic uremic syndrome ( in Japan) https://rrtjournal.biomedcentral.com/articles/10.1186/s41100-016-0088-1 Summary yes
Trigger Raufi 2016 Atypical Hemolytic Uremic Syndrome Secondary to Lupus Nephritis, Responsive to Eculizumab https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062623/ Case Studies yes
Diagnosis Barnard 1965 THE HAEMOLYTIC-URAEMIC SYNDROME OF INFANCY http://journals.co.za/docserver/fulltext/CAJM/11/2/4480.pdf?expires=1503756566&id=id&accname=guest&checksum=2D3223C736894331E2F46DD4D3E73CA9 Case studies yes
Diagnosis Symmer 1952 Thrombotic Microangiopathic Haemolytic Anaemia https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2021829/?page=1 Article yes
Treatment Cheong 2016 Clinical Practice Guidelines for the Management of Atypical Hemolytic Uremic Syndrome in Korea https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999392/ Guidelines yes
Extra Renal Involvement Hofer J 2014 Extra-renal manifestations of complement-mediated thrombotic microangiopathies https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157546/ Article yes
Extra Renal Involvement Ardissino G 2013 Skin Involvement in Atypical Hemolytic Uremic Syndrome https://www.ahusallianceaction.org/wp-content/uploads/2017/05/Ardissino-et-al-AJKD-epub-SKIN.pdf pdf yes
Overview Noris 2016 Genetic Atypical Hemolytic-Uremic Syndrome https://www.ncbi.nlm.nih.gov/books/NBK1367/ NCBI GeneReview yes
Registry Woodward 2016 An innovative and collaborative partnership between patients with rare disease and industry-supported registries: the Global aHUS Registry http://ojrd.biomedcentral.com/articles/10.1186/s13023-016-0537-5 Article yes
Treatment Licht 2015 Efficacy and safety of eculizumab in atypical hemolytic uremic syndrome from 2-year extensions of phase 2 studies. http://www.ncbi.nlm.nih.gov/pubmed/25651309 Study yes
Triggers Yasuda 2016 Postoperative Atypical Hemolytic Uremic Syndrome Treated Successfully with Eculizumab. http://www.ncbi.nlm.nih.gov/pubmed/27150874 Case study yes
Triggers Thadjudeen 2013 A case of atypical hemolytic uremic syndrome successfully treated with eculizumab. http://www.ncbi.nlm.nih.gov/pubmed/24570684 Case study yes
Treatment Fakouri 2013 Atypical hemolytic uremic syndrome: from the rediscovery of complement to targeted therapy. http://www.ncbi.nlm.nih.gov/pubmed/23756030 Study no
Treatment Legendre 2013 Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome. http://www.ncbi.nlm.nih.gov/pubmed/23738544 Trial yes
Treatment Sheerin 2016 A national specialized service in England for atypical haemolytic uraemic syndrome-the first year’s experience. http://www.ncbi.nlm.nih.gov/pubmed/25899302 Study no
Treatment Wong 2015 Patient stratification and therapy in atypical haemolytic uraemic //www.ncbi.nlm.nih.gov/pubmed/26037115syndrome (aHUS). http://www.ncbi.nlm.nih.gov/pubmed/26037115 Study no
Treatment Wong 2015 Anticomplement C5 therapy with eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome. https://www.ncbi.nlm.nih.gov/pubmed/25468487 Lit. no
Treatment Morgan 2015 Complement, a target for therapy in inflammatory and degenerative diseases. http://www.ncbi.nlm.nih.gov/pubmed/26493766 Lit. no
Treatment Kaplan 2014 Current treatment of atypical hemolytic uremic syndrome http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204535/ Study yes
Treatment Richardo 2014 Development of RA101348, a Potent Cyclic Peptide Inhibitor of C5 for Complement-Mediated Diseases http://www.bloodjournal.org/content/124/21/2936 Study yes
Treatment Scully 2014 How I treat thrombotic thrombocytopenic purpura and atypical haemolytic uraemic syndrome http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163720/ Study yes
Treatment Westra 2012 A new era in the diagnosis and treatment of atypical haemolytic uraemic syndrome. http://www.ncbi.nlm.nih.gov/pubmed/22516576 Study no
Treatment Risitano 2011 Design and development of TT30, a novel C3d-targeted C3/C5 convertase inhibitor for treatment of human complement alternative pathway–mediated diseases http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208285/ Study yes
Transplant Xie Tailored eculizumab therapy in the management of complement factor H-mediated atypical hemolytic uremic syndrome in an adult kidney transplant recipient: a case report. http://www.ncbi.nlm.nih.gov/pubmed/23195022 Case study no
Transplant Okumi 2016 Prevention and treatment of atypical hemolytic uremic syndrome after kidney transplantation. http://www.ncbi.nlm.nih.gov/pubmed/26988663 Study no
Transplant Zuber 2012 Eculizumab for atypical hemolytic uremic syndrome recurrence in renal transplantation. http://www.ncbi.nlm.nih.gov/pubmed/22958221 Trial yes
Secondary aHUS de Fontbrun 2015 Use of Eculizumab in Patients With Allogeneic Stem Cell Transplant-Associated Thrombotic Microangiopathy: A Study From the SFGM-TC. http://www.ncbi.nlm.nih.gov/pubmed/25651309 Case study no
Secondary aHUS Jodele 2016 Variable Eculizumab Clearance Requires Pharmacodynamic Monitoring to OptimizeTherapy for Thrombotic Microangiopathy after Hematopoietic Stem Cell Transplantation. http://www.ncbi.nlm.nih.gov/pubmed/26456258 Study no
Secondary aHUS Jodele 2016 The genetic fingerprint of susceptibility for transplant-associated thrombotic microangiopathy. http://www.ncbi.nlm.nih.gov/pubmed/26603840 Study no
Secondary aHUS Li 2015 Clinical characteristics of hemolytic uremic syndrome secondary to cobalamin C disorder in Chinese children. http://www.ncbi.nlm.nih.gov/pubmed/26253414 Case study no
Secondary aHUS Cornec le Gall 2014 Adult-onset eculizumab-resistant hemolytic uremic syndrome associated with cobalamin C deficiency. http://www.ncbi.nlm.nih.gov/pubmed/24210589 Case study no
Secondary aHUS Shiari 2014 Atypical hemolytic-uremic syndrome associated with antiphospholipid antibodies and antiphospholipid syndrome; a novel presentation http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191725/ Case study no
Secondary aHUS Menni 2012 Neonatal atypical hemolytic uremic syndrome due to methylmalonic aciduria and homocystinuria. http://www.ncbi.nlm.nih.gov/pubmed/22447314 Case study no
Secondary aHUS Hale 2005 Hemolytic uremic syndrome after bone marrow transplantation: clinical characteristics and outcome in children. http://www.ncbi.nlm.nih.gov/pubmed/16275594 Study yes
Secondary aHUS Jodele 2014 Eculizumab therapy in children with severe hematopoietic stem cell transplantation-associated thrombotic microangiopathy. http://www.ncbi.nlm.nih.gov/pubmed/24370861/ Case study yes
Registry Licht 2015 The global aHUS registry: methodology and initial patient characteristics. https://www.ncbi.nlm.nih.gov/pubmed/26654630?dopt=Abstract Study yes
Pregnancy Fakouri 2016 Pregnancy-related thrombotic microangiopathies: Clues from complement biology. http://www.ncbi.nlm.nih.gov/pubmed/27158062 Study no
Pregnancy Thomas 2016 How we manage thrombotic microangiopathies in pregnancy. http://www.ncbi.nlm.nih.gov/pubmed/27019232 Study no
Pregnancy Goodship 2010 Pulling the Trigger in Atypical Hemolytic Uremic Syndrome: The Role of Pregnancy http://jasn.asnjournals.org/content/21/5/731.full Study yes
Pregancy Fakouri 2010 Pregnancy-Associated Hemolytic Uremic Syndrome Revisited in the Era of Complement Gene Mutations http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865741/ Study yes
Genetic Causes Warwicker 1998 Genetic studies into inherited and sporadic hemolytic uremic syndrome. http://www.ncbi.nlm.nih.gov/pubmed/9551389 Study yes
Eculizumab Pereira Palma 2016 Critical appraisal of eculizumab for atypical hemolytic uremic syndrome http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835139/ Study yes
Eculizumab Greenbaum 2016 Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndrome. http://www.ncbi.nlm.nih.gov/pubmed/26880462 Trial yes
Eculizumab Fakouri 2014 Insights from the use in clinical practice of eculizumab in adult patients with atypical hemolytic uremic syndrome affecting the native kidneys: an analysis of 19 cases. http://www.ncbi.nlm.nih.gov/pubmed/24021908 Study yes
Diagnosis Akesson 2016 Indications of underdiagnosis of Atypical Hemolytic Uremic Syndrome in a cohort referred to the Coagulation Unit in Malmo, Sweden, for analysis of ADAMTS13 2007-2012. http://www.ncbi.nlm.nih.gov/pubmed/27175932 Study no
Causes Miyata 2016 No association between dysplasminogenemia with p.Ala620Thr mutation and atypical hemolytic uremic syndrome http://www.ncbi.nlm.nih.gov/pubmed/27194432 Study no
Causes Rigothier 2015 Distal Angiopathy and Atypical Hemolytic Uremic Syndrome: Clinical and Functional Properties of an Anti-Factor H IgAλ Antibody. http://www.ncbi.nlm.nih.gov/pubmed/26015278 Case study no
Causes Norris 2015 Podocyte dysfunction in atypical haemolytic uraemic syndrome. http://www.ncbi.nlm.nih.gov/pubmed/25599621 Study no
Causes Mele 2015 Characterization of a New DGKE Intronic Mutation in Genetically Unsolved Cases of Familial Atypical Hemolytic Uremic Syndrome. http://www.ncbi.nlm.nih.gov/pubmed/25854283 Case study no
Causes Bernabeu-Herroro 2015 Complement factor H, FHR-3 and FHR-1 variants associate in an extended haplotype conferring increased risk of atypical hemolytic uremic syndrome. http://www.ncbi.nlm.nih.gov/pubmed/26163426 Study no
Causes Diamante Chiodini 2014 Eculizumab in anti-factor h antibodies associated with atypical hemolytic uremic syndrome. http://www.ncbi.nlm.nih.gov/pubmed/24843055 Case study no
Causes Westland 2014 Phenotypic expansion of DGKE-associated diseases. http://www.ncbi.nlm.nih.gov/pubmed/24511134 Case study yes
Causes Sansbury 2014 Factors determining penetrance in familial atypical haemolytic uraemic syndrome http://www.ncbi.nlm.nih.gov/pubmed/25261570 Study no
Causes Bu 2014 Comprehensive genetic analysis of complement and coagulation genes in atypical hemolytic uremic syndrome. http://www.ncbi.nlm.nih.gov/pubmed/24029428 Study no
Causes Rodriguez de Cordoba 2014 Genetics of atypical hemolytic uremic syndrome (aHUS) http://www.ncbi.nlm.nih.gov/pubmed/24799305 Study no
Causes Meri 2013 Complement activation in diseases presenting with thrombotic microangiopathy. http://www.ncbi.nlm.nih.gov/pubmed/23743117 Study no
Causes Fremeaux- Baachi 2013 Pathophysiology of atypical hemolytic uremic syndrome. Ten years of progress, from laboratory to patient]. http://www.ncbi.nlm.nih.gov/pubmed/24594571 Study no
Causes Dragon-Durey 2010 Clinical features of anti-factor H autoantibody-associated hemolytic uremic syndrome http://www.ncbi.nlm.nih.gov/pubmed/21051740 Study yes
Causes Gasser 1955 [Hemolytic-uremic syndrome: bilateral necrosis of the renal cortex in acute acquired hemolytic anemia]. http://www.ncbi.nlm.nih.gov/pubmed/13274004 Case study no