Article No 344
13 May 2020
A short COVID-19 free quiz about aHUS related stuff. Who can get get 20 out of 20?
| 1. What are the names of the founders of the USA aHUS advocacy organisation The Foundation for Children with Atypical HUS? a. Bert and Chloe Biermann b. Bob and Carol Biermann c. Bill and Cheryl Biermann d. Bret and Charlene Biermann |
| 2. Which is the most common predisposing Complement genetic mutation for aHUS? a. CFB b. MCP/CD46 c. C3 d. CFH |
| 3. Which renal diseases thematic work group in ERKNet represents those with aHUS? a. TMA group b. MAT group c. ATM group d. TAM group |
| 4. What was Complement originally called? a. Alexion b. Alexina c. Alexine d. Alexian |
| 5. In which year was the aHUS alliance created? a. 2012 b. 2013 c. 2014 d. 2015 |
| 6. When it was being developed, what was Ravulizumab known as ? a. ALXN1210 b. ALXN1120 c. ALXN1201 d. ALXN1020 |
| 7. Where is the Mario Negri Institute for Pharmacological Research located? a. Berlin b. Belize c. Berne d. Bergamo |
| 8. Which of the following is NOT a pathway in the Complement system? a. alternative pathway b. systemic pathway c. lectin pathway d. classical pathway |
| 9. What was Alexion Pharmaceuticals’ revenues in 2019, in $ billions ? a. Less than 1 b. Between 2 and 3 c. Between 4 and 5 d. More than 5 |
| 10. What is the date of aHUS Awareness Day a. 20 September b. 24 September c. 25 September d. 27 September |
| 11. Before Conrad von Gasser gave it its name, what was HUS known as? a. TPP b. PTP c. TTP d. PPT |
| 12. At which University is the Database of Complement Gene Variants maintained? a. University College London b. Imperial College London c. King’s College London d. London School of Hygiene and Tropical Medicine |
| 13. In which country is eculizumab finished filled and packaged? a. France b. Germany c. Ireland d. Switzerland |
| 14. Which four letters follow the name ravulizumab? a. cwvz b. czvw c. cvzw d. cwzv |
| 15. On what day did the FDA announce its approval of ravulizumab? a. 9 October 2019 b. 10 October 2019 c. 11 October 2019 d. 18 October 2019 |
| 16. Which other Complement component combines with C3 to make up the C3 convertase in the alternative pathway? a. B b. C2 c. C4 d. C1 |
| 17. Who, in 2020, is the current Chief Executive Officer of Alexion Pharmaceuticals a. David Brennan b. Ludwig Hantson c. Leonard Bell d. David Hallal |
| 18. Which of the following is not a strain of meningitis that is covered by vaccines required before eculizumab/ravulizumab use? a. A b. B c. C d. D |
| 19. What is the maintenance dose of ravulizumab for an adult weighing more than 100kg? a. 3000mg b. 3300mg c. 3600mg d. 3900mg |
| 20. Dr Carla Nester is a renowned aHUS Researcher but based in which country? a. Italy b. Spain c. USA d. Brazil |
Answers below.
Answers
1c, 2d, 3a, 4c, 5b, 6a,7d, 8a, 9c,10b, 11c, 12a, 13c, 14a, 15d, 16b, 17b, 18d, 19c ,20c.
