The previous blog illustrates the difficulty of diagnosing aHUS.
From the basic information about some patients have a go at diagnosing whether following have
A. aHUS ,
B. A secondary form of aHUS
C . “typical” HUS.
- 7 year old with TMA and HUS after receiving chemotherapy for her cancer
- 48 year old with severe high blood pressure and a complaint that they did not have money to further their medication
- 6 year old with TMA and HUS
- 9 year old with TMA and HUS during severe gallstone pancreatitis
- 33 year old with TMA after his stem cell transplant
- 11 year old with history of TMA and HUS and kidney loss in her native kidneys and kidney transplant
- 21 year old with TMA , HUS a butterfly rash , joint pain , joint swelling and an abnormal autoimmune test
- 3 year old with TMA and HUS after he drank unpasteurised apple cider.
- 22 female year old with symptoms of nausea , diarrhoea and acute kidney failure during a localised outbreak of e coli poisoning and with a family history of kidney failure.
- 29 year old with TMA, difficulty speaking and low levels of ADAMTS 13
Acknowledgements to Dr Carla Nester of the University of Iowa for the above case studies 1 to 8 presented at the 2014 aHUS Conference.
See below for decisions made :
Cases 3 , 6 and 9 had aHUS – no other cause of TMA in the first instance and history of TMA /Kidney Disease in the second case and third case
Case 8 had typical HUS
Case 10 had TTP
The remainder of the cases had a secondary form of aHUS
Acknowledgement to Campistol Group for the featured image ( click here for article)